The society was one of the leading tuberculosis sanatoria in the country at the turn of the century founded by a group of immigrant Eastern European Jewish men, many of whom were themselves victims of TB. Headed by Dr. Charles Spivak as Secretary (1904-1927)and by Dr. Philip Hillkowitz as President (1904-1948), sanatorium treated primarily Jewish patients (notably, Solomon Bloomgarden who served as publicity chairman). In 1954 institution changed its mission to cancer research and became American Medical Center; in 1970's renamed AMC Cancer Research Center and Hospital. Today known as AMC Cancer Research Center. Records highlight tuberculosis treatment, immigration and acculturation, and the growth and development of Colorado's Jewish community. The collection includes correspondence, patient records, legal & financial records, scrapbooks, visitor registers, periodicals, minutes, committee reports, newspaper clippings, sound discs, and photographs.

it was called the National Home for Jewish Children in Denver; from 1953-1956, it was the Jewish National Home for Asthmatic Children in Denver; from 1957-1972, it was the Children's Asthma Research Institute and Hospital (CARIH); and from 1973-1977, it became the National Asthma Center. In 1978, it merged with the National Jewish Hospital to become the National Jewish Hospital/National Asthma Center. It started as a residential treatment facility for children with intractable asthma and became a research hospital. The National Asthma Center records include the By-laws, correspondence, memorandums, newspaper clippings, meeting minutes, publications, charts, speeches, financial statements, photographs and miscellaneous materials.

the hospital served Jews and gentiles alike and accepted indigent patients free of charge. The NJH adopted a program that emphasized the benefits of fresh air, good nutrition, and rest. Some of the physicians associated with the hospital included Dr. Saling Simon, Dr. Robert Levy, and Dr. John Elsner. The collection includes correspondence, limited patient records, minutes, financial statements, reports, scrapbooks, and objects from 1899 to 2007. Non-sectarian sanatorium for treatment of tuberculosis opened in 1899 in Denver, Colo. Patients from all over the U.S. were admitted free of charge. With the assistance of the national B'nai B'rith fraternal organization, the hospital was founded by group of Jewish residents of Denver who were of German descent. Early founders included Frances Wisebart Jacobs and Rabbi William Friedman of Denver's Congregation Emmanual. Samuel Grabfelder served as president from 1899-1920; Seraphine Pisko was executive secretary from 1911-1938. In 1997 the organization changed its name to National Jewish Medical and Research Center and focused on lung, allergic and immune diseases. Meeting minutes, annual reports, correspondence, limited patient records, financial records, scrapbooks, photographs and sound discs cover tuberculosis treatment, medical history, immigration and acculturation, Colorado's Jewish community and women's history.