Datasets on employment, earnings, consumer and producer price indexes from U.S. Dept. of Labor, Bureau of Labor Statistics. Go to Data Tools for list of datasets. See Public Data API for tools to retrieve.
"CBP is an annual series that provides subnational economic data by industry. This series includes the number of establishments, employment during the week of March 12, first quarter payroll, and annual payroll."
From the USDA - ERS, this site provides state and county-level data on population, poverty, education, employment, unemployment, and median household income.
Provides fast and easy access to statistical information produced by U.S. Federal agencies, states, private organizations, and major intergovernmental organizations.